Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748891 | 1.00 | KDM4E (0.37) | KDM4EALDH1A1GLADAONOTUM | |
| SCHEMBL4751950 | 0.91 | ALDH1A1 (0.40) | KDM4EALDH1A1GLACYP3A4HPGD | |
| SCHEMBL3304805 | 0.83 | ALDH1A1 (0.41) | KDM4EALDH1A1GLADAONOTUM | |
| SCHEMBL4752664 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1GLADAOCYP3A4 | |
| SCHEMBL3310259 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1GLADAOCYP3A4 | |
| SCHEMBL4751943 | 0.78 | DRD1 (0.34) | CYP3A4CYP2D6LMNADRD1MAPK1 | |
| SCHEMBL3308515 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1GLAHPGDLMNA | |
| SCHEMBL3308910 | 0.73 | MAOA (0.43) | KDM4EALDH1A1GLADAONOTUM | |
| SCHEMBL3308872 | 0.73 | MAOA (0.43) | KDM4EALDH1A1GLADAONOTUM | |
| SCHEMBL3303694 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1GLADAONOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | claimed |
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |