SCHEMBL4748982 — predicted protein targets

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	KIF11	P52732	1/20	0.32

▸	HTR7	P34969	4/20	0.31

▸	BCHE	P06276	1/20	0.31

▸	KDR	P35968	1/20	0.31

▸	ACHE	P22303	1/20	0.30

▸	KDM4E	B2RXH2	1/20	0.30

▸	ALDH1A1	P00352	1/20	0.30

▸	MC4R	P32245	1/20	0.30

▸	MC5R	P33032	1/20	0.30

▸	MC1R	Q01726	1/20	0.30

▸	HTR1A	P08908	1/20	0.30

▸	DRD2	P14416	1/20	0.30

▸	DRD1	P21728	1/20	0.30

▸	DRD4	P21917	1/20	0.30

▸	DRD5	P21918	1/20	0.30

▸	DRD3	P35462	1/20	0.30

▸	MEN1	O00255	1/20	0.30

▸	KMT2A	Q03164	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4025347	0.91	KIF11 (0.37)	KIF11HTR7BCHEKDRACHE
SCHEMBL4023151	0.90	HTR7 (0.37)	KIF11HTR7BCHEKDRACHE
SCHEMBL4748986	0.89	KIF11 (0.32)	KIF11HTR7KDM4EALDH1A1HTR1A
SCHEMBL4019102	0.89	ACHE (0.37)	KIF11HTR7BCHEKDRACHE
SCHEMBL4751959	0.89	KIF11 (0.33)	KIF11HTR7BCHEKDR
SCHEMBL4751648	0.89	KIF11 (0.31)	KIF11HTR7BCHEKDRMC4R
SCHEMBL4751996	0.89	KIF11 (0.31)	KIF11HTR7BCHEKDRKDM4E
SCHEMBL4751647	0.89	KIF11 (0.31)	KIF11HTR7BCHEKDRMC4R
SCHEMBL4749253	0.89	KIF11 (0.32)	KIF11
SCHEMBL4749257	0.89	KIF11 (0.32)	KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008140810-A1	CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS	CYTOKINETICS, INCORPORATED (US)	2008-11-20	—	—	WO	disclosed