Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752003 | 1.00 | BCHE (0.34) | BCHEHTR7SCN9AKDM2BACHE | |
| SCHEMBL4019044 | 1.00 | BCHE (0.34) | BCHEHTR7SCN9AKDM2BACHE | |
| SCHEMBL4022836 | 0.96 | BCHE (0.35) | BCHESCN9AKDM2BTACR1SLC6A5 | |
| SCHEMBL4022533 | 0.96 | BCHE (0.35) | BCHESCN9AKDM2BTACR1SLC6A5 | |
| SCHEMBL13721158 | 0.96 | BCHE (0.35) | BCHESCN9AKDM2BTACR1SLC6A5 | |
| SCHEMBL4028516 | 0.96 | BCHE (0.35) | BCHESCN9AKDM2BTACR1SLC6A5 | |
| SCHEMBL4028513 | 0.96 | BCHE (0.35) | BCHESCN9AKDM2BTACR1SLC6A5 | |
| SCHEMBL4028507 | 0.96 | BCHE (0.35) | BCHESCN9AKDM2BTACR1SLC6A5 | |
| SCHEMBL4749135 | 0.93 | SLC6A5 (0.32) | BCHESCN9AKDM2BACHESLC6A5 | |
| SCHEMBL4751839 | 0.93 | KIF11 (0.34) | HTR7SCN9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |