Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.62 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2612183 | 0.96 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL2612177 | 0.94 | ZDHHC20 (0.71) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL22162999 | 0.94 | ZDHHC20 (0.71) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL2612178 | 0.91 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL1561467 | 0.89 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL2612016 | 0.85 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL19257256 | 0.85 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL632264 | 0.84 | ZDHHC20 (0.75) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A | |
| SCHEMBL25367247 | 0.83 | ZDHHC20 (0.81) | ZDHHC20ZDHHC2MAPK1ALDH1A1TSHR | |
| SCHEMBL111647 | 0.83 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2MAPK1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144545-A1 | SACCHARIDE SENSING SYSTEMS | Carbometrics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |
| US-20160280827-A1 | POLYMERS, HYDROGELS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-09-29 | — | — | US | disclosed |
| WO-2008118626-A9 | INHIBITORS OF JNK AND METHODS FOR IDENTIFYING INHIBITORS OF JNK | BURNHAM INST MEDICAL RESEARCH (US) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008118626-A2 | INHIBITORS OF JNK AND METHODS FOR IDENTIFYING INHIBITORS OF JNK | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280827-A1 | POLYMERS, HYDROGELS, AND USES THEREOF | BOLA2; BOLA2B, PARG, BRAP | ZDHHC20 3660/4885ZDHHC2 3782/4885MAPK1 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.