Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751782 | 0.78 | POLB (0.59) | HSD17B10POLBTSHRRECQLL3MBTL1 | |
| SCHEMBL4303680 | 0.76 | HSD17B10 (0.47) | HSD17B10POLBALDH1A1MGLLNPC1 | |
| SCHEMBL14722845 | 0.75 | RECQL (0.39) | HSD17B10RECQLKDM4EALDH1A1ELANE | |
| SCHEMBL28505046 | 0.73 | ELANE (0.37) | HSD17B10POLBTSHRRECQLL3MBTL1 | |
| SCHEMBL30066427 | 0.72 | KMT2A (0.50) | RECQLKDM4EALDH1A1ELANENPC1 | |
| Oxalic Acid SCHEMBL14810479 | 0.72 | KMO (0.46) | RECQLKDM4EELANENPC1RAB9A | |
| SCHEMBL4553548 | 0.72 | KMT2A (0.50) | RECQLKDM4EALDH1A1ELANENPC1 | |
| SCHEMBL30730294 | 0.71 | NPC1 (0.42) | HSD17B10POLBTSHRL3MBTL1KDM4E | |
| SCHEMBL29350890 | 0.70 | RECQL (0.43) | HSD17B10TSHRRECQLKDM4EALDH1A1 | |
| SCHEMBL878425 | 0.70 | RECQL (0.43) | HSD17B10TSHRRECQLKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |