Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179985 | 0.78 | RAB9A (0.50) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL1811355 | 0.77 | RAB9A (0.49) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL4769593 | 0.76 | MAPT (0.56) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL26477898 | 0.76 | RAB9A (0.51) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL1811356 | 0.76 | RAB9A (0.51) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL30996914 | 0.76 | RAB9A (0.56) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL1669574 | 0.76 | RAB9A (0.56) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL4592965 | 0.74 | RAB9A (0.55) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL1143375 | 0.74 | HSP90AA1 (0.70) | RAB9ANPSR1NPC1MAPTALDH1A1 | |
| SCHEMBL4772518 | 0.74 | RAB9A (0.65) | RAB9ANPSR1NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965645-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070606-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |