Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176051 | 0.88 | HPGD (0.46) | RAB9ANPSR1NPC1MAPTKDM4E | |
| SCHEMBL4176813 | 0.87 | RAB9A (0.38) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL1669574 | 0.79 | RAB9A (0.56) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL30996914 | 0.79 | RAB9A (0.56) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL4752356 | 0.78 | RAB9A (0.47) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL4592965 | 0.78 | RAB9A (0.55) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL1143375 | 0.78 | HSP90AA1 (0.70) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL14327647 | 0.76 | RAB9A (0.53) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL3435395 | 0.76 | RAB9A (0.53) | RAB9ANPSR1NPC1MAPTHSP90AA1 | |
| SCHEMBL20476573 | 0.76 | RAB9A (0.53) | RAB9ANPSR1NPC1MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143410-A1 | Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| CN-101330828-A | Isoxazolines for controlling invertebrate pests | DU PONT (US) | 2008-12-24 | — | — | CN | disclosed |
| EP-1965645-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070606-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143410-A1 | Isoxazolines for Controlling Invertebrate Pests | CBR3, RTN3, HCN3 | RAB9A 629/4885NPSR1 166/4885NPC1 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.