Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281538 | 1.00 | REN (0.38) | RENCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4290984 | 0.90 | SCN9A (0.38) | RENRAB9AKDM4EALDH1A1CCR3 | |
| SCHEMBL4287415 | 0.88 | REN (0.39) | RENCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4281883 | 0.86 | NPC1 (0.43) | CA1CA2CA4CA9RAB9A | |
| SCHEMBL8126494 | 0.85 | CXCR4 (0.45) | CA1CA2CA4CA9RAB9A | |
| SCHEMBL3493396 | 0.83 | TEAD1 (0.46) | RENCA1CA2CA4CA9 | |
| SCHEMBL4290277 | 0.82 | CCR3 (0.39) | RENCA1CA2CA4CA9 | |
| SCHEMBL4752929 | 0.82 | CCR3 (0.39) | RENCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4293711 | 0.81 | PARP1 (0.45) | RENCA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4293709 | 0.81 | PARP1 (0.45) | RENCA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |