Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4290277 | 1.00 | CCR3 (0.39) | CCR3LMNABTKGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL4290984 | 0.90 | SCN9A (0.38) | CCR3GRIN1GRIN2BRENSCN9A | |
| SCHEMBL4753485 | 0.89 | MEN1 (0.38) | CCR3LMNARENCA1CA2 | |
| SCHEMBL4292768 | 0.89 | MEN1 (0.38) | CCR3LMNARENCA1CA2 | |
| SCHEMBL4282069 | 0.89 | ALDH1A1 (0.39) | LMNARENSCN9A | |
| Hydrochloric Acid SCHEMBL4289621 | 0.89 | LMNA (0.48) | LMNACHRNB4CHRNA3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4292929 | 0.86 | HPGD (0.38) | CCR3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4290259 | 0.86 | HTR2C (0.40) | CCR3LMNACHRNB4CHRNA3 | |
| SCHEMBL13705337 | 0.86 | PTGDR2 (0.44) | — | |
| Hydrochloric Acid SCHEMBL4281883 | 0.84 | NPC1 (0.43) | CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |