Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978091 | 0.87 | ALDH1A1 (0.42) | SMN1; SMN2LMNAPOLBATMCYP3A4 | |
| SCHEMBL7380124 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAPOLBSMYD3PTGDR2 | |
| SCHEMBL11181094 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2LMNAPOLBATMCYP3A4 | |
| SCHEMBL11171177 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2LMNAPOLBCYP3A4GRM5 | |
| SCHEMBL1957009 | 0.76 | ESR2 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL28484198 | 0.76 | LMNA (0.49) | SMN1; SMN2LMNAPOLBPTGDR2HRH2 | |
| SCHEMBL3441434 | 0.75 | MEN1 (0.50) | SMN1; SMN2PTGDR2ALDH1A1HPGDKMT2A | |
| SCHEMBL29358931 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAPOLBSMYD3PTGDR2 | |
| SCHEMBL28479832 | 0.74 | LMNA (0.48) | SMN1; SMN2LMNAPOLBHRH2HRH1 | |
| SCHEMBL28484141 | 0.74 | LMNA (0.48) | SMN1; SMN2LMNAPOLBHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |