Hydrochloric Acid

Hydrochloric Acid

SCHEMBL475264

CCC(CC1CO1)[N+](C)(C)C.[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 8/20 0.32
CHRM1 known ✓ P11229 3/20 0.32
CHRM3 known ✓ P20309 4/20 0.31
CHRM5 P08912 6/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CHRM4 P08173 3/20 0.31
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL986959 0.98 CHRM2 (0.33) CHRM2CHRM5CHRM1TSHRMAPK1
SCHEMBL472196 0.70
Hydrochloric Acid SCHEMBL5461997 0.69
SCHEMBL51214 0.69
Hydrochloric Acid SCHEMBL28022294 0.68 CHRM2 (0.31) CHRM2CHRM5CHRM1TSHRMAPK1
SCHEMBL52033 0.67
SCHEMBL6906542 0.66
Hydrochloric Acid SCHEMBL27678606 0.65 ALDH1A1 (0.38) TSHRMAPK1ALDH1A1
SCHEMBL8816548 0.65
Water SCHEMBL5180865 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866341-A1 RAW COTTON LINTERS COMPOSITION, METHOD OF MAKING AND USES THEREOF Hercules Incorporated (US) 2007-12-19 EP claimed
WO-2006107294-A1 RAW COTTON LINTERS COMPOSITION, METHOD OF MAKING AND USES THEREOF HERCULES INCORPORATED (US) 2006-10-12 WO claimed
US-20050228174-A1 Raw cotton linters composition, method of making, and uses thereof HERCULES LLC 2005-10-13 US claimed
EP-0758330-A1 BIPHENYLCARBOXAMIDES USEFUL AS 5-HT1D ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1997-02-19 EP claimed
WO-1995030675-A1 BIPHENYLCARBOXAMIDES USEFUL AS 5-HT1D ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1995-11-16 WO claimed
US-6433026-B1 None US disclosed
EP-3697963-B1 METHOD FOR PRODUCING MULTIPLE PLY PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
EP-3697964-B1 METHOD FOR THE PREPARATION OF SINGLE LAYER OR MULTI-LAYER PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
US-11680371-B2 Method for producing multi-layer paper SOLENIS TECHNOLOGIES, L.P. (US) 2023-06-20 US disclosed
US-11293143-B2 Method for producing single-layer or multi-layer paper SOLENIS TECHNOLOGIES, L.P. (US) 2022-04-05 US disclosed
US-20210222371-A1 METHOD FOR PRODUCING MULTI-LAYER PAPER SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) 2021-07-22 US disclosed
US-20210189658-A1 METHOD FOR PRODUCING SINGLE-LAYER OR MULTI-LAYER PAPER SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) 2021-06-24 US disclosed
EP-0764174-B1 PROCESS FOR REMOVING BILE SALTS FROM A PATIENT AND ALKYLATED COMPOSITIONS THEREFOR GELTEX PHARMA INC (US) 1999-09-01 EP disclosed
US-5917007-A Process for removing bile salts from a patient and alkylated compositions therefor GELTEX PHARMACEUTICALS, INC. (US) 1999-06-29 US disclosed
EP-0909768-A2 Process for removing bile salts from a patient and alkylated compositions therefor GELTEX PHARMACEUTICALS, INC. (US) 1999-04-21 EP disclosed
US-5702696-A FOR TREATMENT OF IRON OVERLOAD DISORDERS GELTEX PHARMACEUTICALS (US) 1997-12-30 US disclosed
US-5693675-A Alkylated amine polymers GELTEX PHARMACEUTICALS INC. (US) 1997-12-02 US disclosed
US-5679717-A Method for removing bile salts from a patient with alkylated amine polymers GELTEX PHARMACEUTICALS, INC. (US) 1997-10-21 US disclosed
EP-0764174-A1 PROCESS FOR REMOVING BILE SALTS FROM A PATIENT AND ALKYLATED COMPOSITIONS THEREFOR GELTEX PHARMACEUTICALS, INC. (US) 1997-03-26 EP disclosed
WO-1995034585-A1 PROCESS FOR REMOVING BILE SALTS FROM A PATIENT AND ALKYLATED COMPOSITIONS THEREFOR GELTEX PHARMACEUTICALS, INC. (US) 1995-12-21 WO disclosed