Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068409 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PARP10PARP3ALDH5A1ABAT | |
| SCHEMBL475275 | 0.92 | ALDH1A1 (0.60) | ALDH1A1PARP10PARP3CYP2A6KDM4E | |
| SCHEMBL28169073 | 0.87 | ALDH1A1 (0.66) | ALDH1A1PARP10PARP3ALDH5A1ABAT | |
| SCHEMBL28665174 | 0.84 | ALDH1A1 (0.61) | ALDH1A1PARP10PARP3ALDH5A1ABAT | |
| SCHEMBL79533 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPT | |
| SCHEMBL21407816 | 0.82 | ALDH1A1 (0.64) | ALDH1A1PARP10PARP3ALDH5A1ABAT | |
| SCHEMBL28156025 | 0.82 | ALDH1A1 (0.64) | ALDH1A1PARP10PARP3ALDH5A1ABAT | |
| SCHEMBL15144900 | 0.82 | ALDH1A1 (0.64) | ALDH1A1PARP10PARP3ALDH5A1ABAT | |
| SCHEMBL28033399 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPT | |
| SCHEMBL28003597 | 0.82 | ALDH1A1 (0.64) | ALDH1A1PARP10PARP3ALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | claimed |
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | claimed |
| EP-1933878-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | Fresenius Kabi Deutschland GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007031266-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | WO | claimed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | disclosed |
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1933878-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | Fresenius Kabi Deutschland GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007031266-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| US-4067857-A | Polyester catalyst system comprising an antimony-containing polycondensation catalyst and an ethylenically unsaturated compound and process employing same | STAUFFER CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | HACL2, AGL, TTL | ALDH1A1 312/4885PARP10 2059/4885PARP3 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.