Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 13/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751666 | 1.00 | MC4R (0.43) | MC4RRENRBP4NTRK1MEN1 | |
| SCHEMBL4776626 | 0.92 | MC4R (0.44) | MC4RRBP4NTRK1MEN1KMT2A | |
| SCHEMBL4776650 | 0.92 | MC4R (0.44) | MC4RRBP4NTRK1MEN1KMT2A | |
| SCHEMBL4751369 | 0.90 | MC4R (0.42) | MC4RRBP4NTRK1MEN1KMT2A | |
| SCHEMBL4751347 | 0.90 | MC4R (0.44) | MC4RRBP4NTRK1MEN1KMT2A | |
| SCHEMBL4774717 | 0.90 | MC4R (0.43) | MC4RNTRK1MEN1KMT2A | |
| SCHEMBL4780053 | 0.89 | MC4R (0.44) | MC4RNTRK1MEN1KMT2A | |
| SCHEMBL4752746 | 0.89 | MC4R (0.44) | MC4RRBP4NTRK1MEN1KMT2A | |
| SCHEMBL4751319 | 0.88 | MC4R (0.41) | MC4RRBP4NTRK1KMT2A | |
| SCHEMBL4794920 | 0.87 | MC4R (0.44) | MC4RRBP4NTRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |