Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776626 | 0.98 | MC4R (0.44) | MC4RALDH1A1TSHRKDM4EPKM | |
| SCHEMBL4774717 | 0.92 | MC4R (0.43) | MC4RALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL4751347 | 0.92 | MC4R (0.44) | MC4RALDH1A1MEN1KMT2ANTRK1 | |
| SCHEMBL4751666 | 0.92 | MC4R (0.43) | MC4RMEN1KMT2ANTRK1RBP4 | |
| SCHEMBL4752905 | 0.92 | MC4R (0.43) | MC4RMEN1KMT2ANTRK1RBP4 | |
| SCHEMBL4779390 | 0.92 | MC4R (0.43) | MC4RALDH1A1LMNAMAPTKDM2B | |
| SCHEMBL4752007 | 0.92 | MC4R (0.45) | MC4RALDH1A1TSHRKDM4EPKM | |
| SCHEMBL4780053 | 0.92 | MC4R (0.44) | MC4RALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4752746 | 0.91 | MC4R (0.44) | MC4RALDH1A1MEN1KMT2ANTRK1 | |
| SCHEMBL4751369 | 0.91 | MC4R (0.42) | MC4RALDH1A1MEN1KMT2ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |