SCHEMBL475308

SCHEMBL475308

CCCCCCCC[SiH2]O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
DNM1 Q05193 5/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585608 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL15662910 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10945722 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL6591537 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL4453137 1.00
SCHEMBL2917398 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL21611875 1.00
SCHEMBL21611856 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL21611861 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL29023773 1.00 TSHR (0.50) TSHRTHRBALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113529417-B Water-based organic silicon permeable anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2023-06-30 CN claimed
US-12378466-B2 Electrochromic display element and method for producing electrochromic display element RICOH COMPANY. LTD. (JP) 2025-08-05 US disclosed
EP-4559887-A1 BASE PROTECTION AGENT KSK Forschung und Entwicklungs GmbH (DE) 2025-05-28 EP disclosed
EP-4512588-A1 WOOD PRESERVATIVE KSK Forschung und Entwicklungs GmbH (DE) 2025-02-26 EP disclosed
US-12091612-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2024-09-17 US disclosed
EP-3945364-B1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC LIGHT CONTROL DEVICE RICOH CO LTD (JP) 2024-09-04 EP disclosed
CN-116716019-B Epoxy heavy-duty anticorrosive paint with efficient BTA targeting effect and preparation method thereof 厦门双瑞船舶涂料有限公司 2024-08-30 CN disclosed
US-11970662-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2024-04-30 US disclosed
CN-112368284-B Electrochromic compound, electrochromic composition and electrochromic element 株式会社理光 2024-03-08 CN disclosed
CN-111164049-B Aerogel and method for producing same 株式会社力森诺科 2024-01-30 CN disclosed
EP-0987007-A2 Emulsifier-free finely dispersed systems of the oil-in-water or water-in-oil type Beiersdorf Aktiengesellschaft (DE) 2000-03-22 EP disclosed
WO-2000007547-A1 FINELY DISPERSED EMULSIFIER-FREE SYSTEMS OF THE OIL-IN-WATER AND WATER-IN-OIL TYPE BEIERSDORF AG (DE) 2000-02-17 WO disclosed
WO-2000007548-A1 FINELY DISPERSED EMULSIFIER-FREE SYSTEMS OF THE OIL-IN-WATER AND WATER-IN-OIL TYPE BEIERSDORF AG (DE) 2000-02-17 WO disclosed
WO-2000007549-A1 FINELY DISPERSED EMULSIFIER-FREE SYSTEMS OF THE OIL-IN-WATER AND WATER-IN-OIL TYPE, CONTAINING BORON NITRIDE BEIERSDORF AG (DE) 2000-02-17 WO disclosed
WO-1999065454-A1 HYDROUS COSMETIC OR PHARMACEUTICAL STICKS BEIERSDORF AG (DE) 1999-12-23 WO disclosed
EP-0870495-A2 Cosmetic washing compositions based on emulsions which do not contain conventional emulsifiers Beiersdorf Aktiengesellschaft (DE) 1998-10-14 EP disclosed
EP-0038571-B1 WATER-RESISTANT REVERSED-PHASE THIN LAYER CHROMATOGRAPHIC PLATE AND A METHOD FOR ITS PREPARATION Shionogi & Co., Ltd. (JP) 1985-10-16 EP disclosed
US-4372850-A A SILICA OR ALUMINA ADSORBENT WITH A TRIALKYLSILYLATED SURFACE SHIONOGI & CO., LTD. (JP) 1983-02-08 US disclosed
EP-0038571-A2 Water-resistant reversed-phase thin layer chromatographic plate and a method for its preparation Shionogi & Co., Ltd. (JP) 1981-10-28 EP disclosed
US-3972982-A EXTRACTION WITH A SILANE AND A HYDROCARBYL AMINE MONSANTO COMPANY (US) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970662-B2 Electrochromic element TMEM109, DSG1, GPX1 TSHR 2752/4885THRB 4504/4885ALDH1A1 2972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.