Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 19/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206944 | 1.00 | GPR84 (0.80) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL296149 | 0.89 | GPR84 (0.82) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL296882 | 0.89 | GPR84 (1.00) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL21615613 | 0.88 | GPR84 (1.00) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL887280 | 0.86 | GPR84 (1.00) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL25484963 | 0.85 | GPR84 (0.75) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL297291 | 0.85 | GPR84 (0.86) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL15079017 | 0.84 | GPR84 (0.84) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL14327762 | 0.84 | GPR84 (0.84) | GPR84MEN1KMT2AKDM4ERECQL | |
| SCHEMBL21615618 | 0.84 | GPR84 (1.00) | GPR84MEN1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292353-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-09-23 | — | — | US | claimed |
| EP-3829565-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | Karlsruher Institut für Technologie (DE) | 2021-06-09 | — | — | EP | claimed |
| WO-2020025488-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | Karlsruher Institut für Technologie (DE) | 2020-02-06 | — | — | WO | claimed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | claimed |
| US-20210292353-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-09-23 | — | — | US | disclosed |
| US-10781172-B2 | Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles | NORTHWESTERN UNIVERSITY (US) | 2020-09-22 | — | — | US | disclosed |
| EP-3350173-B1 | STEREOSELECTIVE PROCESS | BOEHRINGER INGELHEIM INT (DE) | 2020-02-12 | — | — | EP | disclosed |
| US-10189776-B2 | Stereoselective process | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | disclosed |
| WO-2017046355-A1 | STEREOSELECTIVE PROCESS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| WO-2008141077-A1 | PROCESS FOR THE PREPARATION OF TETRAHYDROQUINOLINYL, BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008141077-A1 | PROCESS FOR THE PREPARATION OF TETRAHYDROQUINOLINYL, BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008079427-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-03 | — | — | WO | disclosed |
| US-20070265304-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-15 | — | — | US | disclosed |
| US-20070265304-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265304-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | CETP, NPC1, CES1 | GPR84 2527/4885MEN1 4200/4885KMT2A 2353/4885 |
| US-10189776-B2 | Stereoselective process | CYP4A11, CYP4B1, CYP3A4 | GPR84 2280/4885MEN1 1402/4885KMT2A 4603/4885 |
| US-20170112948-A1 | Inorganic-organic hybrid compound | SLCO4C1, SLCO2A1, SLCO1A2 | GPR84 3061/4885MEN1 1681/4885KMT2A 3120/4885 |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | ICMT, OTC, PNPO | GPR84 3716/4885MEN1 2400/4885KMT2A 2501/4885 |
| US-10781172-B2 | Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles | AADAC, COASY, PAICS | GPR84 2889/4885MEN1 2044/4885KMT2A 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.