Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | SHBG | P04278 | 2/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023741 | 0.90 | CYP3A4 (0.62) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL11021611 | 0.89 | ALDH1A1 (0.61) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL571657 | 0.89 | CYP3A4 (0.61) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL11414100 | 0.86 | ALDH1A1 (0.65) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL23748331 | 0.86 | CYP3A4 (0.71) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL4747201 | 0.86 | CYP3A4 (0.71) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL674222 | 0.86 | CYP3A4 (0.71) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL9640298 | 0.86 | SMN1; SMN2 (0.71) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL7992724 | 0.86 | CYP3A4 (0.71) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL29127389 | 0.85 | CYP3A4 (0.69) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106344233-B | Casing for expansible medical device | W.L.戈尔及同仁股份有限公司 | 2019-07-26 | — | — | CN | disclosed |
| EP-2613842-B1 | INDWELLING LUMINAL DEVICES | GORE & ASS (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9095601-B2 | Cell permeable nanoconjugates of shell-crosslinked knedel (SCK) and peptide nucleic acids (“PNAs”) with uniquely expressed or over-expressed mRNA targeting sequences for early diagnosis and therapy of cancer | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130230452-A1 | CELL PERMEABLE NANOCONJUGATES OF SHELL-CROSSLINKED KNEDEL (SCK) AND PEPTIDE NUCLEIC ACIDS (\"PNAs\") WITH UNIQUELY EXPRESSED OR OVER-EXPRESSED mRNA TARGETING SEQUENCES FOR EARLY DIAGNOSIS AND THERAPY OF CANCER | WASHINGTON UNIVERSITY (US) | 2013-09-05 | — | — | US | disclosed |
| US-8354093-B2 | Cell permeable nanoconjugates of shell-crosslinked knedel (SCK) and peptide nucleic acids (“PNAs”) with uniquely expressed or over-expressed mRNA targeting sequences for early diagnosis and therapy of cancer | WASHINGTON UNIVERSITY (US) | 2013-01-15 | — | — | US | disclosed |
| WO-2008148473-A2 | METHOD FOR THE PRODUCTION OF 17 ALPHA-ACETOXY-6-METHYLENEPREGN-4-ENE-3,20-DIONE, MEDROXYPROGESTERONE ACETATE, AND MEGESTROL ACETATE | BAYER SCHERING PHARMA AG (DE) | 2008-12-11 | — | — | WO | disclosed |
| US-20070207204-A1 | Dosage Form for Time-Varying Patterns of Drug Delivery | ALZA CORPORATION (US) | 2007-09-06 | — | — | US | disclosed |
| US-20060159619-A1 | Cell permeable nanoconjugates of shell-crosslinked knedel (SCK) and peptide nucleic acids (\"PNAs\") with uniquely expressed or over-expressed mRNA targeting sequences for early diagnosis and therapy of cancer | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-07-20 | — | — | US | disclosed |
| WO-2006044716-A2 | CELL PERMEABLE NANOCONJUGATES OF SHELL-CROSSLINKED KNEDEL (SCK) AND PEPTIDE NUCLEIC ACIDS ('PNAs') WITH UNIQUELY EXPRESSED OR OVER-EXPRESSED mRNA TARGETING SEQUENCES FOR EARLY DIAGNOSIS AND THERAPY OF CANCER | WASHINGTON UNIVERSITY IN ST.LOUIS (US) | 2006-04-27 | — | — | WO | disclosed |
| EP-1492509-A1 | DOSAGE FORM PROVIDING TIME-VARYING PATTERNS OF DRUG DELIVERY | ALZA Corporation (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-0300623-A2 | Dispenser with movable matrix comprising a plurality of tiny pills | ALZA CORPORATION (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0297725-A2 | Dispenser with dispersing member for delivering beneficial agent | ALZA CORPORATION (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4783337-A | Osmotic system comprising plurality of members for dispensing drug | ALZA CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| US-4772474-A | Dispenser with internal arrangement of lamina means for dispensing beneficial agent | ALZA CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4729793-A | Composition for manufacturing wall of dispensing device | ALZA CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
| US-4717718-A | Device for the controlled delivery of a beneficial agent | ALZA CORPORATION (US) | 1988-01-05 | — | — | US | disclosed |
| US-4717568-A | Laminar arrangement for increasing delivery of beneficial agent from dispenser | ALZA CORPORATION (US) | 1988-01-05 | — | — | US | disclosed |
| US-4692336-A | Self controlled release device for administering beneficial agent to recipient | ALZA CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| US-4624945-A | Dispensing system with means for increasing delivery of beneficial agent from the system | ALZA CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0054786-B1 | 6-ALPHA-METHYL HYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND THEIR UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |