Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.62 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 2/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571657 | 0.91 | CYP3A4 (0.61) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL18343939 | 0.91 | CYP3A4 (0.65) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4753154 | 0.90 | ALDH1A1 (0.67) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11021611 | 0.86 | ALDH1A1 (0.61) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11414100 | 0.85 | ALDH1A1 (0.65) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11207692 | 0.83 | ALDH1A1 (0.58) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10797873 | 0.83 | CYP3A4 (0.55) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL28352266 | 0.83 | CYP3A4 (0.75) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL23748331 | 0.83 | CYP3A4 (0.71) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL674222 | 0.83 | CYP3A4 (0.71) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054786-B1 | 6-ALPHA-METHYL HYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND THEIR UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |