Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.71 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709778 | 0.84 | CES1 (1.00) | CES1FAAHCPA1CES2AKR1B1 | |
| SCHEMBL1042453 | 0.84 | CES1 (1.00) | CES1FAAHCPA1CES2AKR1B1 | |
| SCHEMBL2266038 | 0.81 | CES1 (0.60) | CES1FAAHCPA1HDAC8HDAC6 | |
| SCHEMBL28434907 | 0.81 | CES1 (0.47) | CES1MEN1KMT2ACNR2 | |
| SCHEMBL51367 | 0.81 | CES1 (0.64) | CES1CES2AKR1B1HDAC8HDAC6 | |
| SCHEMBL1898937 | 0.81 | CES1 (0.50) | CES1CES2AKR1B1HDAC8HDAC6 | |
| SCHEMBL6363616 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1HDAC8HDAC6 | |
| SCHEMBL9111034 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1HDAC8HDAC6 | |
| SCHEMBL7458737 | 0.78 | CES1 (0.52) | CES1CES2AKR1B1HDAC8HDAC6 | |
| SCHEMBL3966085 | 0.77 | AKR1B1 (0.65) | CES1CES2AKR1B1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199375-A1 | SYNTHESIS OF BORON COMPLEXES WITH OXYGEN-CONTAINING MULTIDENTATE LIGANDS | DOW SILICONES CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |
| WO-2008148454-A1 | INVERSE OPALS ON THE BASIS OF LUMINESCENT MATERIALS | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | WO | disclosed |
| EP-1997158-A1 | GAS PHASE INFILTRATION OF LUMINOUS SUBSTANCES INTO THE PORE SYSTEM OF INVERSE OPALS | Merck Patent GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107226-A1 | GAS PHASE INFILTRATION OF LUMINOUS SUBSTANCES INTO THE PORE SYSTEM OF INVERSE OPALS | MERCK PATENT GMBH (DE) | 2007-09-27 | — | — | WO | disclosed |
| EP-0289390-B1 | PROCESS FOR ELIMINATING RADIOACTIVITY FROM EFFLUENTS BY LIQUID-LIQUID EXTRACTION | RHONE-POULENC CHIMIE (FR) | 1991-10-16 | — | — | EP | disclosed |
| US-5006254-A | Extraction with halogenated beta-diketone | RHONE-POULENC CHIMIE (FR) | 1991-04-09 | — | — | US | disclosed |
| EP-0289390-A1 | Process for eliminating radioactivity from effluents by liquid-liquid extraction | RHONE-POULENC CHIMIE (FR) | 1988-11-02 | — | — | EP | disclosed |