Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.39 |
| ▸ | CTSB | P07858 | 5/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753954 | 0.88 | CTSL (0.41) | CTSKCTSBCTSLCTSSHSP90AA1 | |
| SCHEMBL4751288 | 0.88 | CTSK (0.44) | CTSKCTSBRENCTSLCTSS | |
| SCHEMBL4753911 | 0.87 | CTSK (0.40) | CTSKCTSBRENCTSLCTSS | |
| SCHEMBL4753917 | 0.87 | SYK (0.40) | CTSKCTSBCTSLCTSSHSP90AA1 | |
| SCHEMBL4753912 | 0.87 | CTSK (0.39) | CTSKCTSBRENCTSLCTSS | |
| SCHEMBL8107196 | 0.84 | CTSK (0.47) | CTSKCTSBRENCTSLCTSS | |
| SCHEMBL4751645 | 0.84 | CTSK (0.47) | CTSKCTSBRENCTSLCTSS | |
| SCHEMBL4751609 | 0.80 | CTSL (0.41) | CTSKCTSBCTSLCTSSHSP90AA1 | |
| SCHEMBL4751711 | 0.79 | SYK (0.41) | CTSKCTSBCTSLCTSSHSP90AA1 | |
| SCHEMBL8104698 | 0.73 | CTSL (0.46) | CTSKCTSBCTSLCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |