Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2046004 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL5883547 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL15110823 | 0.78 | KDM4E (0.68) | ALDH1A1HPGDMEN1POLBKMT2A | |
| SCHEMBL15120926 | 0.78 | KDM4E (0.51) | ALDH1A1FDPSHPGDMEN1KMT2A | |
| SCHEMBL15110824 | 0.78 | KDM4E (0.68) | ALDH1A1HPGDMEN1POLBKMT2A | |
| SCHEMBL4262772 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL140472 | 0.77 | ALDH1A1 (0.70) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL1966450 | 0.77 | ALDH1A1 (0.70) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL7074229 | 0.77 | TTR (0.55) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL3952495 | 0.77 | PTGS1 (0.57) | ALDH1A1TSHRAOX1FDPSHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412706-A2 | NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2012-02-01 | — | — | EP | disclosed |