SCHEMBL140472

SCHEMBL140472

COc1cc(C=O)ccc1OC(F)F

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.70
TSHR P16473 1/20 0.70
FDPS P14324 1/20 0.60
KDM4E B2RXH2 3/20 0.57
HTT P42858 2/20 0.57
PDE4B Q07343 1/20 0.57
TTR P02766 1/20 0.55
AOX1 Q06278 1/20 0.54
TRIM24 O15164 1/20 0.54
HPGD P15428 1/20 0.54
ALDH5A1 P51649 1/20 0.54
ABAT P80404 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1966450 0.93 ALDH1A1 (0.70) ALDH1A1TSHRFDPSKDM4EHTT
SCHEMBL140841 0.89 DRD1 (0.53) ALDH1A1TSHRFDPSKDM4EHTT
SCHEMBL29440132 0.89 DRD1 (0.53) ALDH1A1TSHRFDPSKDM4EHTT
SCHEMBL1414783 0.87 ALDH1A1 (0.66) ALDH1A1TSHRFDPSKDM4EHTT
SCHEMBL7538876 0.85 ALDH1A1 (0.49) ALDH1A1TSHRFDPSKDM4EHTT
SCHEMBL1159006 0.84 ALDH1A1 (0.72) ALDH1A1TSHRFDPSKDM4EHTT
3,4-Dimethoxybenzaldehyde SCHEMBL29364994 0.83 ALDH1A1 (1.00) ALDH1A1TSHRFDPSKDM4EHTT
3,4-Dimethoxybenzaldehyde SCHEMBL5308959 0.83 ALDH1A1 (1.00) ALDH1A1TSHRFDPSKDM4EHTT
3,4-Dimethoxybenzaldehyde SCHEMBL25202 0.83 ALDH1A1 (1.00) ALDH1A1TSHRFDPSKDM4EHTT
3,4-Dimethoxybenzaldehyde SCHEMBL1330962 0.83 ALDH1A1 (1.00) ALDH1A1TSHRFDPSKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546665-A Preparation method and application of acidizing corrosion inhibitor suitable for multi-medium acid 山东滨州昱诚化工科技有限公司 2024-08-27 CN claimed
US-20260124173-A1 THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS INC (US) 2026-05-07 US disclosed
US-20250304533-A1 THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-10-02 US disclosed
US-12410128-B1 Therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-09-09 US disclosed
US-20250197394-A1 ANTIBACTERIALS BASED ON MONOCYCLIC FRAGMENTS COUPLED TO AMINOPIPERIDINE NAPHTHYRIDINE SCAFFOLD UNIVERZA V LJUBLJANI (SI) 2025-06-19 US disclosed
WO-2025101939-A1 THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2025-05-15 WO disclosed
CN-118546665-A Preparation method and application of acidizing corrosion inhibitor suitable for multi-medium acid 山东滨州昱诚化工科技有限公司 2024-08-27 CN disclosed
CN-117924277-A Oxime ether compound and preparation method, pharmaceutical composition and application thereof 中国药科大学 2024-04-26 CN disclosed
US-20230270703-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF EYE DISORDERS OCCURX PTY LTD (AU) 2023-08-31 US disclosed
US-20230270703-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF EYE DISORDERS OCCURX PTY LTD (AU) 2023-08-31 US disclosed
CN-1953975-A 2, 6 bisheteroaryl-4-aminopyrimidines as adenosine receptor antagonists ALMIRALL PRODESFARMA AG (CH) 2007-04-25 CN disclosed
EP-1697351-A1 2,6-BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS Almirall Prodesfarma AG (CH) 2006-09-06 EP disclosed
US-20050239841-A1 New compounds BIOVITRUM AB (SE) 2005-10-27 US disclosed
WO-2005058883-A1 2, 6 BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS ALMIRALL PRODESFARMA AG (CH) 2005-06-30 WO disclosed
WO-2005051381-A1 Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) BIOVITRUM AB (SE) 2005-06-09 WO disclosed
JP-2004002247-A METHOD FOR PRODUCING 4-DIFLUOROMETHOXY-3-HYDROXYBENZALDEHYDE DAIKIN IND LTD 2004-01-08 JP disclosed
EP-0706513-B1 FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS BYK GULDEN LOMBERG CHEM FAB (DE) 2002-05-15 EP disclosed
US-5712298-A Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-01-27 US disclosed
EP-0706513-A1 FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1996-04-17 EP disclosed
WO-1995001338-A1 FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1995-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304533-A1 THERAPEUTIC ALKALOID COMPOUNDS HTR3B, MTNR1B, PNMT ALDH1A1 2227/4885TSHR 4064/4885FDPS 2651/4885
US-20260124173-A1 THERAPEUTIC ALKALOID COMPOUNDS ADRA1B, HTR1B, ADRB1 ALDH1A1 903/4885TSHR 194/4885FDPS 4393/4885
US-20230270703-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF EYE DISORDERS ALDH1A2, RBP4, RARB ALDH1A1 264/4885TSHR 846/4885FDPS 533/4885
US-20250197394-A1 ANTIBACTERIALS BASED ON MONOCYCLIC FRAGMENTS COUPLED TO AMINOPIPERIDINE NAPHTHYRIDINE SCAFFOLD NPEPPS, MFN2, DNM1 ALDH1A1 4356/4885TSHR 4808/4885FDPS 283/4885
US-12410128-B1 Therapeutic alkaloid compounds HTR3B, MTNR1B, PNMT ALDH1A1 2227/4885TSHR 4064/4885FDPS 2651/4885
US-20050239841-A1 New compounds MCHR1, NPY1R, HCRTR1 ALDH1A1 1918/4885TSHR 60/4885FDPS 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.