Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104699 | 0.90 | CTSL (0.53) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL4753468 | 0.87 | SYK (0.46) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL2679219 | 0.83 | CTSL (0.62) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL7286508 | 0.83 | CTSL (0.62) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL2679221 | 0.83 | CTSL (0.62) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL4751711 | 0.82 | SYK (0.41) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL4753917 | 0.81 | SYK (0.40) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL8104698 | 0.81 | CTSL (0.46) | SYKCTSLCTSSCTSBCTSK | |
| SCHEMBL4751645 | 0.78 | CTSK (0.47) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL8107196 | 0.78 | CTSK (0.47) | CTSLCTSSCTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |