Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150167 | 0.95 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL3223716 | 0.95 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL7595607 | 0.95 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL5919483 | 0.95 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL7151040 | 0.95 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL7151383 | 0.95 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB | |
| Propylene Glycol SCHEMBL6265783 | 0.84 | TDP1 (0.53) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL16556818 | 0.79 | LMNA (0.40) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL14432954 | 0.79 | LMNA (0.40) | TDP1LMNAALDH1A1TSHRTHRB | |
| SCHEMBL31544633 | 0.78 | LMNA (0.44) | TDP1LMNAALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156330-A1 | USE OF XANTHORRHIZOL FOR ANTI-WRINKLE TREATMENT | BIOCARE CO., LTD. (KR) | 2008-12-24 | — | — | WO | disclosed |