Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3466569 | 0.99 | SCD (0.50) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL4753765 | 0.84 | HCRTR1 (0.44) | SCDCYP2C9CYP2C19MGLLP2RX7 | |
| Hydrochloric Acid SCHEMBL3466376 | 0.83 | HCRTR1 (0.43) | SCDCYP2C9CYP2C19MGLLP2RX7 | |
| Hydrochloric Acid SCHEMBL3468340 | 0.82 | RBP4 (0.53) | SCD | |
| SCHEMBL1222719 | 0.79 | SCD (0.53) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL4262448 | 0.78 | CYP2C9 (0.63) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL4753844 | 0.77 | SCD (0.47) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2820604 | 0.77 | SCD (0.58) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL14172993 | 0.76 | SCD (0.59) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL13983799 | 0.76 | SCD (0.62) | SCDCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |