Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3466376 | 0.99 | HCRTR1 (0.43) | HCRTR1HCRTR2SCDP2RX7HDAC8 | |
| SCHEMBL4753470 | 0.84 | SCD (0.51) | SCDP2RX7MGLLCYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL3466569 | 0.83 | SCD (0.50) | SCDP2RX7MGLLCYP2C9CYP2C19 | |
| SCHEMBL4772658 | 0.82 | CACNA2D1 (0.39) | HCRTR1HCRTR2SCDP2RX7SCN5A | |
| Hydrochloric Acid SCHEMBL3466281 | 0.82 | SCN5A (0.51) | SCDP2RX7HDAC8SCN5ASCN9A | |
| SCHEMBL4775889 | 0.81 | SCN5A (0.42) | HCRTR1HCRTR2SCDP2RX7HDAC8 | |
| SCHEMBL4774662 | 0.80 | CACNA1B (0.41) | HCRTR1HCRTR2SCDHDAC8SCN5A | |
| Hydrochloric Acid SCHEMBL3468340 | 0.79 | RBP4 (0.53) | SCDPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4837579 | 0.79 | SCD (0.38) | HCRTR1HCRTR2SCDP2RX7HDAC8 | |
| SCHEMBL2820773 | 0.79 | HCRTR1 (0.48) | HCRTR1HCRTR2SCDP2RX7MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |