Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 7/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753878 | 0.90 | CYP2C9 (0.47) | SCDDCTPP1MAPK8MAPK10CYP2C9 | |
| SCHEMBL4753491 | 0.89 | SCN5A (0.38) | SCN5ASCN9ASMOSCDEPHX2 | |
| Hydrochloric Acid SCHEMBL3467141 | 0.88 | SCN5A (0.38) | SCN5ASCN9ASMOSCDEPHX2 | |
| SCHEMBL4753766 | 0.85 | SCD5 (0.42) | SCN5ASCN9ASCDEPHX2 | |
| SCHEMBL1221107 | 0.82 | SCN5A (0.44) | SCN5ASCN9ASMOSCDDCTPP1 | |
| SCHEMBL3466775 | 0.79 | SCN5A (0.46) | SCN5ASCN9AHTR2B | |
| Hydrochloric Acid SCHEMBL3466605 | 0.79 | SCN5A (0.45) | SCN5ASCN9AHTR2B | |
| Hydrochloric Acid SCHEMBL4755658 | 0.77 | SMO (0.43) | SCN5ASCN9ASMOSCDCYP2C9 | |
| SCHEMBL13059058 | 0.76 | SMO (0.44) | SCN5ASCN9ASMOSCDPPARG | |
| Hydrochloric Acid SCHEMBL4755567 | 0.76 | SCD (0.44) | SMOSCDDCTPP1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |