Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.42 |
| ▸ | SCD | O00767 | 4/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753477 | 0.92 | SCD5 (0.46) | SCD5SCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4753472 | 0.85 | SCN5A (0.47) | SCDSCN5ASCN9AEPHX2 | |
| SCHEMBL1222564 | 0.84 | SCD5 (0.44) | SCD5SCDEPHX2NPC1RAB9A | |
| SCHEMBL4753491 | 0.76 | SCN5A (0.38) | SCDSCN5ASCN9AEPHX2 | |
| Hydrochloric Acid SCHEMBL3467141 | 0.76 | SCN5A (0.38) | SCDSCN5ASCN9AEPHX2 | |
| SCHEMBL1221687 | 0.76 | SCD (0.49) | SCD5SCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1221577 | 0.75 | SCD5 (0.49) | SCD5SCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4753878 | 0.75 | CYP2C9 (0.47) | SCD | |
| SCHEMBL4753765 | 0.72 | HCRTR1 (0.44) | SCDSCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL3466376 | 0.72 | HCRTR1 (0.43) | SCDSCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | claimed |
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |