Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | WNT3 | P56703 | 1/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894957 | 0.92 | SMO (0.41) | SMOBACE1BACE2TSHRHTT | |
| SCHEMBL1222764 | 0.82 | SMO (0.40) | SMOBACE1BACE2USP30MEN1 | |
| SCHEMBL1222810 | 0.82 | CYP2C9 (0.45) | TSHRHTTMEN1KMT2ASCD | |
| SCHEMBL12894959 | 0.79 | SMO (0.44) | SMOSMN1; SMN2LMNACETPSCD | |
| Hydrochloric Acid SCHEMBL4755565 | 0.76 | SMO (0.44) | SMOSMN1; SMN2LMNACETPMEN1 | |
| Hydrochloric Acid SCHEMBL4755567 | 0.76 | SCD (0.44) | SMOSCD | |
| SCHEMBL1221107 | 0.75 | SCN5A (0.44) | SMOLMNAMEN1KMT2ASCD | |
| SCHEMBL12894671 | 0.75 | SMO (0.42) | SMOSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL224423 | 0.72 | GPR119 (0.49) | LMNAMEN1KMT2ASCDHCRTR1 | |
| SCHEMBL4755595 | 0.72 | FFAR1 (0.45) | LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |