Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 5/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050230 | 0.92 | MEN1 (0.46) | HDAC3HDAC1HDAC2NCOR2LMNA | |
| SCHEMBL4753983 | 0.89 | PPARG (0.44) | MMP12MMP13PPARGPPARAHDAC3 | |
| SCHEMBL12894955 | 0.86 | HDAC3 (0.51) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL31407633 | 0.85 | GAA (0.40) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL31407335 | 0.85 | TAAR1 (0.41) | FFAR1PPARGPPARAHDAC3HDAC1 | |
| SCHEMBL31407623 | 0.84 | PPARA (0.44) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL30724412 | 0.84 | HDAC1 (0.49) | MMP12HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4073146 | 0.83 | FFAR1 (0.46) | FFAR1MMP12MMP13MMP2MMP9 | |
| SCHEMBL6676419 | 0.83 | L3MBTL1 (0.43) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7730448 | 0.80 | HDAC1 (0.45) | HDAC3HDAC1HDAC2NCOR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |