Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529444 | 0.81 | ACHE (0.49) | MAPTPOLBMAPK1HIF1AACHE | |
| SCHEMBL4090716 | 0.81 | MAPT (0.51) | MAPTPOLBMAPK1MEN1KMT2A | |
| SCHEMBL16038390 | 0.76 | SMN1; SMN2 (0.45) | MAPTHIF1AACHEMEN1KMT2A | |
| SCHEMBL1083778 | 0.75 | CYP2D6 (0.63) | MAPTMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL4753568 | 0.75 | CYP1A2 (0.63) | MAPTPOLBMAPK1MEN1KMT2A | |
| SCHEMBL4090718 | 0.75 | PDE5A (0.63) | MAPTPOLBLMNASMN1; SMN2GBA1 | |
| SCHEMBL4090714 | 0.75 | MAPT (0.42) | MAPTPOLBMAPK1HIF1AACHE | |
| SCHEMBL4090989 | 0.73 | HIF1A (0.76) | MAPTMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL4085263 | 0.72 | HIF1A (0.79) | MAPTMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL15452624 | 0.72 | ABCG2 (0.65) | MAPTMAPK1LMNAGBA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |