Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | USP1 | O94782 | 3/20 | 0.43 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753567 | 0.81 | MAPT (0.41) | MAPTMAPK1POLBMEN1KMT2A | |
| SCHEMBL4090718 | 0.75 | PDE5A (0.63) | MAPTPOLBLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL14529444 | 0.73 | ACHE (0.49) | MAPTMAPK1POLBMEN1KMT2A | |
| SCHEMBL4753568 | 0.73 | CYP1A2 (0.63) | MAPTMAPK1POLBMEN1KMT2A | |
| SCHEMBL4090714 | 0.72 | MAPT (0.42) | MAPTMAPK1POLBMEN1KMT2A | |
| SCHEMBL16038390 | 0.71 | SMN1; SMN2 (0.45) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1083778 | 0.70 | CYP2D6 (0.63) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL4090989 | 0.68 | HIF1A (0.76) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL1042337 | 0.68 | ACHE (0.51) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL1083874 | 0.68 | MAPK1 (1.00) | MAPTMAPK1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | CNR2, CNR1, GPR18 | MAPT 4125/4885MAPK1 2435/4885POLB 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.