SCHEMBL475371

SCHEMBL475371

CC(OC(C)c1cccc(C(C)(C)C)c1)c1cccc(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
ACHE P22303 3/20 0.40
KIF11 P52732 3/20 0.39
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
SLC6A4 P31645 5/20 0.36
HTR2C P28335 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750571 0.86 HDAC4 (0.39) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL9245588 0.85 HDAC8 (0.42) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL598661 0.81 KIF11 (0.49) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL1787675 0.80 ACHE (0.45) HDAC4HDAC2HDAC8ACHEALDH1A1
SCHEMBL17449153 0.79 ACHE (0.50) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL1787680 0.79 ACHE (0.44) HDAC4HDAC2HDAC8ACHERXRA
SCHEMBL24473629 0.78 ACHE (0.45) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL18793694 0.78 HDAC4 (0.41) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL475370 0.78 HDAC4 (0.46) HDAC4HDAC2HDAC8ACHEKIF11
SCHEMBL15836405 0.78 ACHE (0.49) HDAC4HDAC2HDAC8ACHEKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112624996-B Oxazoline derivative containing sulfonate structure, preparation thereof and application thereof in control of phytophagous mites 南开大学 2022-11-11 CN disclosed
CN-104926623-A Preparation method for etoxazole intermediate 3-tert-butylphenylethylether SHANGHAI CAC CHEMICAL CO LTD 2015-09-23 CN disclosed
CN-104926623-A Preparation method for etoxazole intermediate 3-tert-butylphenylethylether SHANGHAI CAC CHEMICAL CO LTD 2015-09-23 CN disclosed
CN-104557480-A Synthetic method of 3-tert-butylphenylethylether SHANGHAI SHENGNONG PESTICIDE CO LTD 2015-04-29 CN disclosed
CN-104557480-A Synthetic method of 3-tert-butylphenylethylether SHANGHAI SHENGNONG PESTICIDE CO LTD 2015-04-29 CN disclosed
CN-104557480-A Synthetic method of 3-tert-butylphenylethylether SHANGHAI SHENGNONG PESTICIDE CO LTD 2015-04-29 CN disclosed
CN-103113318-A New etoxazole compound, preparation method and acaricidal activity thereof NANJING UNIVERSITY OF TECHNOLOGY 2013-05-22 CN disclosed
EP-2411564-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2012-02-01 EP disclosed
WO-2010108874-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2010-09-30 WO disclosed