Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.41 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499183 | 0.85 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL23818006 | 0.82 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL11414694 | 0.70 | MAPT (0.62) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL25455111 | 0.69 | ALDH1A1 (0.76) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL11771699 | 0.69 | ALDH1A1 (0.56) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL10272675 | 0.69 | HSD17B10 (0.60) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL23818000 | 0.69 | ALDH1A1 (0.72) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL25455165 | 0.69 | ALDH1A1 (0.70) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL11401275 | 0.68 | ALDH1A1 (0.55) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL11422402 | 0.68 | HSD17B10 (0.67) | ALDH1A1RAB9ASMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |