Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755633 | 1.00 | NPSR1 (0.38) | NPSR1RAB9ALMNAPTGDR2RECQL | |
| SCHEMBL4753739 | 0.76 | ESR1 (0.32) | PTGDR2POLBMAPTALDH1A1GAA | |
| SCHEMBL4753740 | 0.76 | ESR1 (0.32) | PTGDR2POLBMAPTALDH1A1GAA | |
| SCHEMBL4753774 | 0.73 | SMN1; SMN2 (0.38) | PTGDR2POLBPI4KBKMT2A | |
| SCHEMBL4753772 | 0.73 | SMN1; SMN2 (0.38) | PTGDR2POLBPI4KBKMT2A | |
| SCHEMBL6058686 | 0.73 | MAPT (0.50) | RECQLPOLBMAPTALDH1A1MEN1 | |
| SCHEMBL28548543 | 0.73 | GAA (0.37) | NPSR1RAB9ARECQLPOLBTP53 | |
| SCHEMBL28548541 | 0.73 | GAA (0.37) | NPSR1RAB9ARECQLPOLBTP53 | |
| SCHEMBL13713079 | 0.71 | NPSR1 (0.47) | NPSR1LMNATP53ALOX15MAPT | |
| SCHEMBL20100423 | 0.70 | GLA (0.34) | RAB9APTGDR2POLBPI4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |