⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646052 | 1.00 | — | — | |
| SCHEMBL80842 | 1.00 | — | — | |
| SCHEMBL348692 | 0.92 | — | — | |
| SCHEMBL4955059 | 0.92 | — | — | |
| SCHEMBL9549203 | 0.90 | CYP2D6 (0.38) | — | |
| SCHEMBL518834 | 0.90 | CYP2D6 (0.38) | — | |
| SCHEMBL82934 | 0.90 | — | — | |
| SCHEMBL518712 | 0.85 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL519521 | 0.85 | — | — | |
| SCHEMBL676844 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924275-B1 | THIO-CONTAINING INHIBITORS OF AMINOPEPTIDASE P, COMPOSITIONS THEREOF AND METHOD OF USE | SIMMONS WILLIAM H (US) | 2012-08-08 | — | — | EP | claimed |
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | claimed |
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | claimed |
| US-7390789-B2 | Thio-containing inhibitors of aminopeptidase P, and compositions thereof | SIMMONS WILLIAM H | 2008-06-24 | — | — | US | claimed |
| WO-2007066099-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-06-14 | — | — | WO | claimed |
| US-20070060525-A1 | Thio-containing inhibitors of aminopeptidase P, compositions thereof and method of use | SIMMONS WILLIAM H | 2007-03-15 | — | — | US | claimed |
| US-5962686-A | FUNGICIDES | HOFFMANN-LA ROCHE INC. (US) | 1999-10-05 | — | — | US | claimed |
| US-5900486-A | FUNGICIDES | HOFFMANN-LA ROCHE INC. (US) | 1999-05-04 | — | — | US | claimed |
| EP-0647228-B1 | ASYMMETRIC HYDROGENATION OF FUROIMIDAZOLE DERIVATIVES | LONZA AG (CH) | 1996-06-26 | — | — | EP | claimed |
| US-5434269-A | Asymmetric hydrogenation of furoimidazole derivatives | LONZA LTD. (CH) | 1995-07-18 | — | — | US | claimed |
| EP-0647228-A1 | ASYMMETRIC HYDROGENATION OF FUROIMIDAZOLE DERIVATIVES. | LONZA AG (CH) | 1995-04-12 | — | — | EP | claimed |
| WO-1994024137-A1 | ASYMMETRIC HYDROGENATION OF FUROIMIDAZOLE DERIVATIVES | LONZA LTD. (CH) | 1994-10-27 | — | — | WO | claimed |
| CN-104364246-B | Piperidine derivatives useful as GPR119 agonists | 株式会社钟根堂 | 2018-05-22 | — | — | CN | disclosed |
| EP-2412706-B1 | NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2014-10-29 | — | — | EP | disclosed |
| US-8466161-B2 | Hydroxamate derivative, a production method for the same, and a pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-06-18 | — | — | US | disclosed |
| EP-1924275-B1 | THIO-CONTAINING INHIBITORS OF AMINOPEPTIDASE P, COMPOSITIONS THEREOF AND METHOD OF USE | SIMMONS WILLIAM H (US) | 2012-08-08 | — | — | EP | disclosed |
| US-5434269-A | Asymmetric hydrogenation of furoimidazole derivatives | LONZA LTD. (CH) | 1995-07-18 | — | — | US | disclosed |
| EP-0647228-A1 | ASYMMETRIC HYDROGENATION OF FUROIMIDAZOLE DERIVATIVES. | LONZA AG (CH) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994024137-A1 | ASYMMETRIC HYDROGENATION OF FUROIMIDAZOLE DERIVATIVES | LONZA LTD. (CH) | 1994-10-27 | — | — | WO | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |