⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519521 | 1.00 | — | — | |
| SCHEMBL27646052 | 0.85 | — | — | |
| SCHEMBL475384 | 0.85 | — | — | |
| SCHEMBL80842 | 0.85 | — | — | |
| SCHEMBL4955059 | 0.83 | — | — | |
| SCHEMBL348692 | 0.83 | — | — | |
| SCHEMBL82934 | 0.81 | — | — | |
| SCHEMBL9549203 | 0.81 | CYP2D6 (0.38) | — | |
| SCHEMBL518707 | 0.81 | — | — | |
| SCHEMBL16611766 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061024-B2 | Combination analgesic employing opioid agonist and neutral antagonist | AIKO BIOTECHNOLOGY (US) | 2015-06-23 | — | — | US | claimed |
| US-20140336212-A1 | Combination Analgesic Employing Opioid Agonist and Neutral Antagonist | AIKO BIOTECHNOLOGY (US) | 2014-11-13 | — | — | US | claimed |
| US-8883817-B2 | Combination analgesic employing opioid and neutral antagonist | AIKO BIOTECHNOLOGY (US) | 2014-11-11 | — | — | US | claimed |
| US-8748448-B2 | Combination analgesic employing opioid agonist and neutral antagonist | AIKO BIOTECHNOLOGY (US) | 2014-06-10 | — | — | US | claimed |
| US-20130090350-A1 | Combination Analgesic Employing Opioid Agonist and Neutral Antagonist | AIKO BIOTECHNOLOGY (US) | 2013-04-11 | — | — | US | claimed |
| EP-2214672-A2 | COMBINATION ANALGESIC EMPLOYING OPIOID AND NEUTRAL ANTAGONIST | Aiko Biotechnology (US) | 2010-08-11 | — | — | EP | claimed |
| WO-2009051824-A2 | COMBINATION ANALGESIC EMPLOYING OPIOID AND NEUTRAL ANTAGONIST | AIKO BIOTECHNOLOGY (US) | 2009-04-23 | — | — | WO | claimed |
| EP-1294705-B1 | SYNTHESIS OF CYCLIC COMPOUNDS | BIOSIGNAL LTD (AU) | 2008-09-10 | — | — | EP | claimed |
| EP-1294705-A4 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LTD (AU) | 2005-02-09 | — | — | EP | claimed |
| US-20040110966-A1 | Synthesis of cyclic compounds | UNISEARCH LIMITED (AU) | 2004-06-10 | — | — | US | claimed |
| EP-1294705-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2003-03-26 | — | — | EP | claimed |
| WO-2002000639-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2002-01-03 | — | — | WO | claimed |
| US-6214841-B1 | ANTICOAGULANTS | ELI LILLY AND COMPANY | 2001-04-10 | — | — | US | claimed |
| EP-0884326-A2 | Antithrombitic compound | ELI LILLY AND COMPANY (US) | 1998-12-16 | — | — | EP | claimed |
| WO-1998051684-A1 | ANTITHROMBOTIC COMPOUND | ELI LILLY AND COMPANY (US) | 1998-11-19 | — | — | WO | claimed |
| US-9061024-B2 | Combination analgesic employing opioid agonist and neutral antagonist | AIKO BIOTECHNOLOGY (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140336212-A1 | Combination Analgesic Employing Opioid Agonist and Neutral Antagonist | AIKO BIOTECHNOLOGY (US) | 2014-11-13 | — | — | US | disclosed |
| EP-0884326-A2 | Antithrombitic compound | ELI LILLY AND COMPANY (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1998051684-A1 | ANTITHROMBOTIC COMPOUND | ELI LILLY AND COMPANY (US) | 1998-11-19 | — | — | WO | disclosed |
| US-5698522-A | INHIBIT RELEASE OF LUTEINIZING HORMONE RELEASING HORMONE | ABBOTT LABORATORIES (US) | 1997-12-16 | — | — | US | disclosed |