⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646052 | 1.00 | — | — | |
| SCHEMBL475384 | 1.00 | — | — | |
| SCHEMBL348692 | 0.92 | — | — | |
| SCHEMBL4955059 | 0.92 | — | — | |
| SCHEMBL9549203 | 0.90 | CYP2D6 (0.38) | — | |
| SCHEMBL518834 | 0.90 | CYP2D6 (0.38) | — | |
| SCHEMBL82934 | 0.90 | — | — | |
| SCHEMBL518712 | 0.85 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL519521 | 0.85 | — | — | |
| SCHEMBL676844 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | claimed |
| US-20230398529-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-14 | — | — | US | claimed |
| EP-4229040-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | Bayer Aktiengesellschaft (DE) | 2023-08-23 | — | — | EP | claimed |
| US-11702431-B2 | Oxo-substituted compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-18 | — | — | US | claimed |
| CN-116348452-A | Asymmetric transfer hydrogenation of 2-aryl substituted bicyclic pyridones in the presence of chiral ruthenium catalysts | 拜耳公司 | 2023-06-27 | — | — | CN | claimed |
| US-20230167117-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEONE MEDICINES I GMBH (CH) | 2023-06-01 | — | — | US | claimed |
| US-20230167109-A1 | Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation | UNIV EMORY (US) | 2023-06-01 | — | — | US | claimed |
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-20230038124-A1 | NOVEL SUBSTITUTED CONDENSED RING COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2023-02-09 | — | — | US | claimed |
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | claimed |
| WO-1995032217-A1 | PEPTIDE ANTAGONIST INTERMEDIATES OF NEUROTENSIN | RHONE-POULENC RORER S.A. (FR) | 1995-11-30 | — | — | WO | claimed |
| WO-1995032218-A1 | NEUROTENSIN ANTAGONIST PEPTIDES | RHONE-POULENC RORER S.A. (FR) | 1995-11-30 | — | — | WO | claimed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | claimed |
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | claimed |
| EP-0169812-B1 | PHOSPHATIDYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | claimed |
| EP-0099057-B1 | N-ACYL DERIVATIVES OF PEPTIDES, THEIR MANUFACTURE AND USE IN COMBATING DISEASES AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | claimed |
| US-4610817-A | N-acyl derivatives of peptides, their preparation and their use in the treatment of disorders, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | claimed |
| EP-0169812-A1 | Phosphatidyl compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1986-01-29 | — | — | EP | claimed |
| EP-0099057-A2 | N-acyl derivatives of peptides, their manufacture and use in combating diseases and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | claimed |