SCHEMBL475385

SCHEMBL475385

O=C[C@@H]1CCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2267946 1.00
SCHEMBL80843 1.00
Hydrochloric Acid SCHEMBL28298516 0.97
SCHEMBL28164332 0.95 SLC6A2 (0.33)
Ethane SCHEMBL28373914 0.95
SCHEMBL3679748 0.92
SCHEMBL348693 0.92
SCHEMBL4955062 0.92
Hydrochloric Acid SCHEMBL21056375 0.90 SLC6A2 (0.33)
Hydrochloric Acid SCHEMBL21056373 0.90 SLC6A2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 865 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118667752-A Cell culture method for producing human bone morphogenetic protein 安济盛生物医药有限公司 2024-09-20 CN claimed
EP-4351719-A1 MODULATION OF COASY EXPRESSION EMPIRICO INC. (US) 2024-04-17 EP claimed
CN-114805505-A Surface protein ProH of corynebacterium crenatum and application of surface protein ProH in surface display system 江西师范大学 2022-07-29 CN claimed
WO-2019011879-A1 THERAPEUTIC FOR TREATING CAPILLARY LEAK SYNDROME HENNING RAINER (CH) 2019-01-17 WO claimed
US-8524654-B2 Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation THE UAB RESEARCH FOUNDATION (US) 2013-09-03 US claimed
EP-1713780-B1 NOVEL INHIBITORS OF GLUTAMINYL CYCLASE PROBIODRUG AG (DE) 2012-01-18 EP claimed
JP-4806628-B2 2011-11-02 JP claimed
EP-2338490-A2 Combinations Useful for the Treatment of Neuronal Disorders Probiodrug AG (DE) 2011-06-29 EP claimed
WO-2011032159-A1 METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT META COMESTICS, LLC (US) 2011-03-17 WO claimed
US-7897633-B2 Neuronal disorders such as Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophrenia, impaired food intake, sleep-wakefulness, impaired homeostatic regulation of energy metabolism, impaired autonomic function; alcoholism PROBIODRUG AG (DE) 2011-03-01 US claimed
US-4956380-A COGNITION ACTIVATORS ONO PHARMACEUTICAL CO., LTD. (JP) 1990-09-11 US claimed
EP-0384341-A2 New proline derivatives KABUSHIKI KAISHA YAKULT HONSHA (JP) 1990-08-29 EP claimed
EP-0154353-B1 AN ANTI-AMNESTIC AGENT KABUSHIKI KAISHA YAKULT HONSHA (JP) 1989-11-15 EP claimed
EP-0287036-A2 New pharmaceutical compositions comprising esters or amides as active ingredients ONO PHARMACEUTICAL CO., LTD. (JP) 1988-10-19 EP claimed
EP-0277588-A1 Prolinal derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-08-10 EP claimed
EP-0275482-A2 Proline derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-07-27 EP claimed
EP-0268190-A1 Prolinal derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-05-25 EP claimed
US-4687778-A Anti-amnestic agent KABUSHIKI KAISHA YAKULT HONSHA (JP) 1987-08-18 US claimed
EP-0203865-A1 Process for the separation of antifactor VIII:C antibodies, especially for use in the blood plasma purification of a type A haemophiliac Jozefowicz, Marcel (FR) 1986-12-03 EP claimed
EP-0154353-A2 An anti-amnestic agent KABUSHIKI KAISHA YAKULT HONSHA (JP) 1985-09-11 EP claimed