⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267946 | 1.00 | — | — | |
| SCHEMBL475385 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28298516 | 0.97 | — | — | |
| SCHEMBL28164332 | 0.95 | SLC6A2 (0.33) | — | |
| Ethane SCHEMBL28373914 | 0.95 | — | — | |
| SCHEMBL3679748 | 0.92 | — | — | |
| SCHEMBL348693 | 0.92 | — | — | |
| SCHEMBL4955062 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL21056375 | 0.90 | SLC6A2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL21056373 | 0.90 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3284 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | claimed |
| CN-117567498-A | Sodium hydride suspension and application thereof in flow chemical reaction | 武汉药明康德新药开发有限公司 | 2024-02-20 | — | — | CN | claimed |
| US-20230398529-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-14 | — | — | US | claimed |
| CN-117069063-A | Sodium hydride suspension and application thereof in flow chemical reaction | 武汉药明康德新药开发有限公司 | 2023-11-17 | — | — | CN | claimed |
| EP-4229040-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | Bayer Aktiengesellschaft (DE) | 2023-08-23 | — | — | EP | claimed |
| US-11702431-B2 | Oxo-substituted compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-18 | — | — | US | claimed |
| CN-116348452-A | Asymmetric transfer hydrogenation of 2-aryl substituted bicyclic pyridones in the presence of chiral ruthenium catalysts | 拜耳公司 | 2023-06-27 | — | — | CN | claimed |
| CN-113651767-B | Benzisoxazole heterocyclic compound and preparation method and application thereof | 江西中医药大学 | 2023-06-09 | — | — | CN | claimed |
| US-20230167117-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEONE MEDICINES I GMBH (CH) | 2023-06-01 | — | — | US | claimed |
| US-20230167109-A1 | Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation | UNIV EMORY (US) | 2023-06-01 | — | — | US | claimed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | claimed |
| EP-0154353-B1 | AN ANTI-AMNESTIC AGENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-11-15 | — | — | EP | claimed |
| EP-0169812-B1 | PHOSPHATIDYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | claimed |
| EP-0287036-A2 | New pharmaceutical compositions comprising esters or amides as active ingredients | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-10-19 | — | — | EP | claimed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |
| EP-0275482-A2 | Proline derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-07-27 | — | — | EP | claimed |
| EP-0268190-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | claimed |
| US-4687778-A | Anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1987-08-18 | — | — | US | claimed |
| EP-0169812-A1 | Phosphatidyl compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1986-01-29 | — | — | EP | claimed |
| EP-0154353-A2 | An anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-09-11 | — | — | EP | claimed |