Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755285 | 0.92 | MAPT (0.52) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4753657 | 0.92 | MEN1 (0.52) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4755874 | 0.88 | HIF1A (0.67) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4753636 | 0.82 | KMT2A (0.55) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4091224 | 0.82 | HIF1A (0.71) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4756892 | 0.80 | MAPT (0.61) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4754220 | 0.79 | MEN1 (0.54) | MAPTLMNAALDH1A1KMT2ATSHR | |
| SCHEMBL4099593 | 0.79 | HIF1A (0.51) | MAPTHIF1ALMNAALDH1A1KMT2A | |
| SCHEMBL4756771 | 0.79 | MEN1 (0.49) | MAPTALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL4753639 | 0.78 | MAPT (0.61) | MAPTHIF1ALMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |