Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755874 | 0.87 | HIF1A (0.67) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL4753639 | 0.85 | MAPT (0.61) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL4753586 | 0.84 | KMT2A (0.56) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL1084285 | 0.84 | HIF1A (0.67) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL1083836 | 0.84 | HIF1A (0.71) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL4755939 | 0.83 | ABCG2 (0.50) | MAPTLMNAALDH1A1TSHRABCG2 | |
| SCHEMBL1083838 | 0.83 | MAPT (0.65) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL1083777 | 0.83 | HIF1A (0.73) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL4756735 | 0.82 | KMT2A (0.58) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL4754092 | 0.82 | MEN1 (0.58) | MAPTHIF1ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |