Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755906 | 0.89 | HIF1A (0.56) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4753852 | 0.88 | MAPT (0.50) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4756892 | 0.87 | MAPT (0.61) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4754102 | 0.86 | KMT2A (0.72) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4753639 | 0.85 | MAPT (0.61) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4755285 | 0.84 | MAPT (0.52) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4755891 | 0.84 | LMNA (0.53) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL1083814 | 0.81 | HIF1A (0.97) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL1084817 | 0.81 | HIF1A (0.92) | HIF1AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4755935 | 0.81 | MAPT (0.56) | MAPTLMNAALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |