Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740671 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL4740700 | 0.78 | ADRB2 (0.45) | ADRB2ADRB1DRD3 | |
| SCHEMBL4739373 | 0.76 | ADRB2 (0.42) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL2818621 | 0.75 | ADRB2 (0.49) | ADRB2ADRB1 | |
| SCHEMBL1683032 | 0.74 | ADRB2 (0.50) | ADRB2ADRB1DRD2 | |
| SCHEMBL3583805 | 0.73 | ADRB2 (0.70) | ADRB2 | |
| SCHEMBL3582127 | 0.73 | ADRB2 (0.82) | ADRB2 | |
| SCHEMBL3592056 | 0.73 | ADRB2 (0.82) | ADRB2 | |
| SCHEMBL14166418 | 0.72 | ABCB11 (0.54) | ADRB2ADRB1DRD3DRD2 | |
| SCHEMBL3582804 | 0.71 | ADRB2 (0.68) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149110-A1 | BICYCLOR [2.2.1] HEPT-7-YLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES AND CONDITIONS IN WHICH M3 MUSCARINIC RECEPTOR ACTIVITY AND BETA-ADRENERGIC ACTIVITY ARE IMPLICATED | ARGENTA DISCOVERY LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |