Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752964 | 0.90 | CCR3 (0.51) | PRKCIMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29669427 | 0.89 | IDO1 (0.44) | MAPK14MAPK13MAPK12MAPK11IDO1 | |
| SCHEMBL4677288 | 0.82 | PRKCI (0.53) | PRKCIJAK2JAK1PRMT5IDO1 | |
| SCHEMBL1868695 | 0.82 | DDB1 (0.55) | PRKCIMAPK14JAK2JAK1PRMT5 | |
| SCHEMBL15833600 | 0.82 | PRKCI (0.53) | PRKCIMAPK14JAK2JAK1PRMT5 | |
| SCHEMBL15825750 | 0.82 | PRKCI (0.53) | PRKCIMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL18787932 | 0.79 | PRKCI (0.50) | PRKCIMAPK14JAK2JAK1PRMT5 | |
| SCHEMBL18211616 | 0.79 | PRKCI (0.50) | PRKCIMAPK14JAK2JAK1PRMT5 | |
| SCHEMBL3290233 | 0.78 | DRD2 (0.57) | PRKCIMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3092780 | 0.78 | PRKCI (0.44) | PRKCIMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |