Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751550 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL6592897 | 0.90 | — | — | |
| SCHEMBL7920161 | 0.81 | F2R (0.38) | F2RALDH1A1 | |
| SCHEMBL7920157 | 0.81 | F2R (0.38) | F2RALDH1A1 | |
| SCHEMBL4751864 | 0.80 | — | — | |
| SCHEMBL1157522 | 0.75 | ALDH1A1 (0.33) | F2RALDH1A1 | |
| SCHEMBL1011943 | 0.75 | ADH1A (0.33) | F2RALDH1A1 | |
| SCHEMBL9636568 | 0.75 | CYP1A2 (0.34) | F2RCYP1A2CYP2D6 | |
| SCHEMBL15556533 | 0.75 | — | — | |
| Trimethylammonium SCHEMBL28806004 | 0.73 | ADH1A (0.39) | F2RCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510500-A | Preparation method of asperazepanones alkaloid and application of asperazepanones alkaloid as anti-inflammatory drug | 中国海洋大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-116726010-A | Application of macrolide derivative in preparation of medicines for inhibiting pro-inflammatory cytokine acting agents | 中国海洋大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-112851622-B | Macrolide brefeldin A ester derivative and application thereof | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112851622-A | Macrolide brefeldin A ester derivative and application thereof | 中国海洋大学 | 2021-05-28 | — | — | CN | disclosed |
| EP-3013424-A1 | METHODS AND COMPOSITIONS FOR MODULATING CANCER STEM CELLS | University of Canberra (AU) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014205511-A1 | METHODS AND COMPOSITIONS FOR MODULATING CANCER STEM CELLS | UNIVERSITY OF CANBERRA (AU) | 2014-12-31 | — | — | WO | disclosed |
| WO-2008149962-A1 | THIOIMIDATE COMPOUND AND USE THEREOF FOR CONTROLLING PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-12-11 | — | — | WO | disclosed |
| US-4631272-A | N-acylated 1-alkylamino-1-deoxy-ketose derivatives, a process for their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |
| EP-0152856-A2 | N-acylated 1-alkylamimo-1-desoxy ketose derivatives, method for their preparation and use | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |