Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255655 | 0.79 | SIRT2 (0.48) | SIRT2ALDH1A1HTR6PDE4APDE4B | |
| SCHEMBL4754296 | 0.78 | SIRT2 (0.61) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL7441184 | 0.78 | F2RL3 (0.55) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL27550167 | 0.74 | CREBBP (0.47) | SIRT2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10325495 | 0.74 | KDM4E (0.50) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5359539 | 0.73 | MAPT (0.58) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL5355132 | 0.72 | F2RL3 (0.62) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL5622616 | 0.71 | SMN1; SMN2 (0.60) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL8166825 | 0.71 | SIRT2 (0.68) | SIRT2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5357541 | 0.71 | SIRT2 (0.53) | SIRT2MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963689-A | ANTIEMETICS, ANALGESICS, GASTROINTESTINAL DISORDERS, SCHIZOPHRENIA | PFIZER INC. (US) | 1990-10-16 | — | — | US | claimed |