Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754296 | 0.89 | SIRT2 (0.61) | F2RL3SIRT2KCNH2DYRK1AMEN1 | |
| SCHEMBL5355132 | 0.82 | F2RL3 (0.62) | F2RL3SIRT2KCNH2DYRK1AMEN1 | |
| SCHEMBL5357642 | 0.78 | F2RL3 (0.58) | F2RL3SIRT2KCNH2DYRK1AMEN1 | |
| SCHEMBL7441180 | 0.78 | SIRT2 (0.53) | F2RL3SIRT2MEN1ALDH1A1TSHR | |
| SCHEMBL12260323 | 0.76 | F2RL3 (0.49) | F2RL3SIRT2KCNH2DYRK1AMEN1 | |
| SCHEMBL10325497 | 0.73 | KDM4E (0.51) | KCNH2DYRK1APOLBHTR6PDE4A | |
| Propionic Acid SCHEMBL19133584 | 0.72 | F2RL3 (0.64) | F2RL3SIRT2KCNH2DYRK1AMEN1 | |
| SCHEMBL28742332 | 0.72 | L3MBTL1 (0.68) | MEN1ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7113697 | 0.72 | POLB (0.74) | MEN1ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL3131200 | 0.72 | IMPDH2 (0.57) | DYRK1AALDH1A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963689-A | ANTIEMETICS, ANALGESICS, GASTROINTESTINAL DISORDERS, SCHIZOPHRENIA | PFIZER INC. (US) | 1990-10-16 | — | — | US | claimed |