Sugi Predict

Sugi Predict / Compounds / SCHEMBL4754377

SCHEMBL4754377

SCHEMBL4754377

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nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.55
▸ TSHR P16473 6/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ TDP1 Q9NUW8 2/20 0.38
▸ CNR1 P21554 1/20 0.38
▸ ADRA1A P35348 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ ABCC3 O15438 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45286 1.00 LMNA (0.55) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL14609335 0.96 LMNA (0.52) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL3076831 0.96 LMNA (0.52) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL5907137 0.88 LMNA (0.52) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL4445441 0.84 LMNA (0.50) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL7145506 0.84 LMNA (0.64) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL1613784 0.84 LMNA (0.64) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL15800764 0.84 LMNA (0.50) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL4276778 0.84 LMNA (0.50) LMNATSHRALDH1A1TDP1CNR1
SCHEMBL4448890 0.82 LMNA (0.48) LMNATSHRALDH1A1TDP1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008155619-A2 PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS PFIZER INC. (US) 2008-12-24 — — WO disclosed