Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45286 | 0.96 | LMNA (0.55) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL4754377 | 0.96 | LMNA (0.55) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL14609335 | 0.92 | LMNA (0.52) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL5907137 | 0.92 | LMNA (0.52) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL4276778 | 0.81 | LMNA (0.50) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL7145506 | 0.81 | LMNA (0.64) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL1613784 | 0.81 | LMNA (0.64) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL15800764 | 0.81 | LMNA (0.50) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL4445441 | 0.81 | LMNA (0.50) | LMNATSHRTDP1CNR1ADRA1A | |
| SCHEMBL4448890 | 0.79 | LMNA (0.48) | LMNATSHRTDP1CNR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214462-A2 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017214335-A1 | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | SHIONOGI & CO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-8440281-B2 | Stabilized blends of polyester and polyamide | BASF SE (DE) | 2013-05-14 | — | — | US | disclosed |
| US-20100233405-A1 | Stabilized Blends of Polyester and Polyamide | CIBA CORPORATION (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100233406-A1 | Stabilized Blends of Polyester and Polyamide | CIBA CORPORATION (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2007127639-A2 | PRODRUG DERIVATIVES OF ACIDS USING ALCOHOLS WITH HOMOTOPIC HYDROXY GROUPS AND METHODS FOR THEIR PREPARATION AND USE | AERIE PHARMACEUTICALS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | AERIE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| EP-1355986-B1 | POLYESTER COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SC HOLDING AG (CH) | 2007-01-24 | — | — | EP | disclosed |
| EP-1440117-B1 | POLYESTER AND POLYAMIDE COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SC HOLDING AG (CH) | 2006-12-27 | — | — | EP | disclosed |
| EP-1440117-A2 | POLYESTER AND POLYAMIDE COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | Ciba SC Holding AG (CH) | 2004-07-28 | — | — | EP | disclosed |
| EP-1355986-A1 | POLYESTER COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | Ciba SC Holding AG (CH) | 2003-10-29 | — | — | EP | disclosed |
| US-20030139497-A1 | Polyester and polyamide compositions of low residual aldehyde content | CIBA SPECIALTY CHEMICALS CORP. | 2003-07-24 | — | — | US | disclosed |
| WO-2003031507-A2 | POLYESTER AND POLYAMIDE COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-17 | — | — | WO | disclosed |
| US-20020198297-A1 | Polyester and polyamide compositions of low residual aldehyde content | ODORISIO PAUL A (US) | 2002-12-26 | — | — | US | disclosed |
| US-20020137856-A1 | Polyester compositions of low residual aldehyde content | CIBA SPECIALTY CHEMICALS CORP. | 2002-09-26 | — | — | US | disclosed |
| EP-1239006-A1 | Polyester and polyamide compositions of low residual aldehyde content | Ciba SC Holding AG (CH) | 2002-09-11 | — | — | EP | disclosed |
| WO-2002053643-A1 | POLYESTER COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-07-11 | — | — | WO | disclosed |
| US-5681879-A | BLEND OF POLYESTER, POLYHYDRIC ALCOHOL, SYNERGISTIC MIXTURE OF INORGANIC AND HALOGEN FLAME RETARDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0691370-A2 | Flame-retardant polyester resin composition | Mitsubishi Chemical Corporation (JP) | 1996-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | P2RX3, P2RX7, P2RX2 | LMNA 3635/4885TSHR 737/4885TDP1 4738/4885 |
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | HCAR1, HCAR2, PAICS | LMNA 3188/4885TSHR 2474/4885TDP1 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.